KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOS2
All Species:
30.91
Human Site:
S1047
Identified Species:
68
UniProt:
Q07890
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07890
NP_008870.2
1332
152979
S1047
P
N
T
G
R
H
G
S
T
S
G
T
L
R
G
Chimpanzee
Pan troglodytes
XP_515425
1598
179688
T1314
P
S
N
P
R
P
G
T
M
R
H
P
T
P
L
Rhesus Macaque
Macaca mulatta
XP_001099864
1331
152695
S1047
P
N
T
G
R
H
G
S
T
S
G
T
L
R
G
Dog
Lupus familis
XP_547804
1363
156214
S1078
P
N
T
G
R
H
G
S
T
S
G
T
L
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q02384
1333
153108
S1048
P
N
A
G
R
H
G
S
T
S
G
T
L
R
G
Rat
Rattus norvegicus
NP_001129033
1333
153157
S1048
P
N
A
S
R
H
G
S
T
S
G
T
F
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515100
1332
152934
S1047
P
N
A
G
R
H
G
S
T
S
G
T
L
R
G
Chicken
Gallus gallus
XP_421461
1466
167231
S1182
P
N
A
G
R
H
G
S
T
S
G
T
L
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_690171
1343
153249
G1047
P
V
R
Q
A
V
G
G
G
G
T
L
K
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26675
1596
177916
T1096
K
P
R
R
Q
N
Q
T
N
S
S
S
K
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782335
1310
150821
S1044
P
S
S
N
R
H
M
S
L
V
G
T
S
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.7
99
93.2
N.A.
94.9
94.6
N.A.
91.1
78.9
N.A.
73
N.A.
39.8
N.A.
N.A.
52.1
Protein Similarity:
100
68.5
99.7
95.5
N.A.
97.9
97.4
N.A.
95.9
84.7
N.A.
83.9
N.A.
55.1
N.A.
N.A.
68
P-Site Identity:
100
20
100
100
N.A.
93.3
80
N.A.
93.3
86.6
N.A.
13.3
N.A.
6.6
N.A.
N.A.
46.6
P-Site Similarity:
100
33.3
100
100
N.A.
93.3
80
N.A.
93.3
86.6
N.A.
13.3
N.A.
33.3
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
55
0
0
82
10
10
10
73
0
0
10
55
% G
% His:
0
0
0
0
0
73
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
10
0
0
10
55
10
19
% L
% Met:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% M
% Asn:
0
64
10
10
0
10
0
0
10
0
0
0
0
0
0
% N
% Pro:
91
10
0
10
0
10
0
0
0
0
0
10
0
10
0
% P
% Gln:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
10
82
0
0
0
0
10
0
0
0
73
0
% R
% Ser:
0
19
10
10
0
0
0
73
0
73
10
10
10
0
19
% S
% Thr:
0
0
28
0
0
0
0
19
64
0
10
73
10
0
0
% T
% Val:
0
10
0
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _